DIETA CETOGÉNICA: ¿UNA OPCIÓN SALUDABLE O SOLO UNA MODA?
DOI:
https://doi.org/10.32399/icuap.rdic.2448-5829.2025.32.1596Palabras clave:
Dieta cetogénica, Carbohidratos, Metabolismo, Pérdida de peso, DeporteResumen
La dieta cetogénica, o "keto," es un plan de alimentación bajo en carbohidratos y alto en grasas que cambia la fuente de energía del cuerpo de la glucosa a la grasa mediante un estado metabólico llamado cetosis. Desarrollada en la década de 1920 para tratar la epilepsia, esta dieta se ha popularizado por sus posibles beneficios en la pérdida de peso, el manejo de la diabetes y algunas condiciones neurológicas. Sin embargo, no es ideal para todos, especialmente para adolescentes, ya que sus restricciones pueden llevar a deficiencias nutricionales. Aunque algunos deportistas pueden beneficiarse de la mayor oxidación de grasa para deportes de resistencia, el entrenamiento de alta intensidad generalmente requiere carbohidratos. La dieta cetogénica puede ser útil bajo supervisión médica, pero debe adoptarse con cautela. En última instancia, una dieta balanceada y un estilo de vida activo son esenciales para una salud a largo plazo.
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Alhamzah, S. A., Gatar, O. M., & Alruwaili, N. W. (2023). Effects of ketogenic diet on oxidative stress and cancer: A literature review. Advances In Cancer Biology - Metastasis, 7, 100093. https://doi.org/10.1016/j.adcanc.2023.100093
Andrewski, E., Cheng, K., & Vanderpool, C. (2022). Nutritional Deficiencies in Vegetarian, Gluten-Free, and Ketogenic Diets. Pediatrics in review, 43(2), 61–70. https://doi.org/10.1542/pir.2020-004275
Ashtary-Larky, D., Bagheri, R., Bavi, H., Baker, J. S., Moro, T., Mancin, L., & Paoli, A. (2022). Ketogenic diets, physical activity and body composition: a review. The British journal of nutrition, 127(12), 1898–1920. https://doi.org/10.1017/S0007114521002609
Basolo, A., Magno, S., Santini, F., & Ceccarini, G. (2022). Ketogenic Diet and Weight Loss: Is There an Effect on Energy Expenditure?. Nutrients, 14(9), 1814. https://doi.org/10.3390/nu14091814
Boden, G., Sargrad, K., Homko, C., Mozzoli, M., & Stein, T. P. (2005). Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes. Annals of internal medicine, 142(6), 403–411. https://doi.org/10.7326/0003-4819-142-6-200503150-00006
Bostock, E. C. S., Kirkby, K. C., Taylor, B. V., & Hawrelak, J. A. (2020). Consumer Reports of "Keto Flu" Associated With the Ketogenic Diet. Frontiers in nutrition, 7, 20. https://doi.org/10.3389/fnut.2020.00020
Crosby, L., Davis, B., Joshi, S., Jardine, M., Paul, J., Neola, M., & Barnard, N. D. (2021). Ketogenic Diets and Chronic Disease: Weighing the Benefits Against the Risks. Frontiers in nutrition, 8, 702802. https://doi.org/10.3389/fnut.2021.702802
Kim J. M. (2017). Ketogenic diet: Old treatment, new beginning. Clinical neurophysiology practice, 2, 161–162. https://doi.org/10.1016/j.cnp.2017.07.001
D'Andrea Meira, I., Romão, T. T., Pires do Prado, H. J., Krüger, L. T., Pires, M. E. P., & da Conceição, P. O. (2019). Ketogenic Diet and Epilepsy: What We Know So Far. Frontiers in neuroscience, 13, 5. https://doi.org/10.3389/fnins.2019.00005
Dhillon KK, Gupta S. Biochemistry, Ketogenesis. [Updated 2023 Feb 6]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK493179/
Erickson, N., Boscheri, A., Linke, B., & Huebner, J. (2017). Systematic review: isocaloric ketogenic dietary regimes for cancer patients. Medical oncology (Northwood, London, England), 34(5), 72. https://doi.org/10.1007/s12032-017-0930-5
Goldberg, E. L., Shchukina, I., Asher, J. L., Sidorov, S., Artyomov, M. N., & Dixit, V. D. (2020). Ketogenesis activates metabolically protective γδ T cells in visceral adipose tissue. Nature metabolism, 2(1), 50–61. https://doi.org/10.1038/s42255-019-0160-6
Fink, J., Schoenfeld, B. J., & Nakazato, K. (2018). The role of hormones in muscle hypertrophy. The Physician and sportsmedicine, 46(1), 129–134. https://doi.org/10.1080/00913847.2018.1406778
Masood W, Annamaraju P, Khan Suheb MZ, et al. Ketogenic Diet. [Updated 2023 Jun 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK499830/
Mooli, R. G. R., & Ramakrishnan, S. K. (2022). Emerging Role of Hepatic Ketogenesis in Fatty Liver Disease. Frontiers in physiology, 13, 946474. https://doi.org/10.3389/fphys.2022.946474
Nakao, R., Abe, T., Yamamoto, S., & Oishi, K. (2019). Ketogenic diet induces skeletal muscle atrophy via reducing muscle protein synthesis and possibly activating proteolysis in mice. Scientific reports, 9(1), 19652. https://doi.org/10.1038/s41598-019-56166-8
Nelson, D. L., & Cox, M. M. (2009). Lehninger. Principios de bioquímica. http://repositoriobibliotecas.uv.cl/handle/uvscl/1513
Paoli, A., Bianco, A., & Grimaldi, K. A. (2015). The Ketogenic Diet and Sport: A Possible Marriage?. Exercise and sport sciences reviews, 43(3), 153–162. https://doi.org/10.1249/JES.0000000000000050
Paoli, A., Mancin, L., Bianco, A., Thomas, E., Mota, J. F., & Piccini, F. (2019). Ketogenic Diet and Microbiota: Friends or Enemies?. Genes, 10(7), 534. https://doi.org/10.3390/genes10070534
Paoli, A.; Cenci, L.; Pompei, P.; Sahin, N.; Bianco, A.; Neri, M.; Caprio, M.; Moro, T. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders. Nutrients 2021, 13, 374. https://doi.org/10.3390/nu13020374
Paoli, A.; Bianco, A.; Moro, T.; Mota, J.F.; Coelho-Ravagnani, C.F. The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg? Nutrients 2023, 15, 3120. https://doi.org/10.3390/nu15143120
Tabaie, E. A., Reddy, A. J., & Brahmbhatt, H. (2021). A narrative review on the effects of a ketogenic diet on patients with Alzheimer's disease. AIMS public health, 9(1), 185–193. https://doi.org/10.3934/publichealth.2022014
Ting, R., Dugré, N., Allan, G. M., & Lindblad, A. J. (2018). Ketogenic diet for weight loss. Canadian family physician Medecin de famille canadien, 64(12), 906.
Vargas, S., Romance, R., Petro, J. L., Bonilla, D. A., Galancho, I., Espinar, S., Kreider, R. B., & Benítez-Porres, J. (2018). Efficacy of ketogenic diet on body composition during resistance training in trained men: a randomized controlled trial. Journal of the International Society of Sports Nutrition, 15(1), 31. https://doi.org/10.1186/s12970-018-0236-9
Volek, J. S., Phinney, S. D., Forsythe, C. E., Quann, E. E., Wood, R. J., Puglisi, M. J., Kraemer, W. J., Bibus, D. M., Fernandez, M. L., & Feinman, R. D. (2009). Carbohydrate restriction has a more favorable impact on the metabolic syndrome than a low fat diet. Lipids, 44(4), 297–309. https://doi.org/10.1007/s11745-008-3274-2
Williams, T. J., & Cervenka, M. C. (2017). The role for ketogenic diets in epilepsy and status epilepticus in adults. Clinical neurophysiology practice, 2, 154-160.
Yoshida, T., & Delafontaine, P. (2020). Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy. Cells, 9(9), 1970. https://doi.org/10.3390/cells9091970
Zajac, A., Poprzecki, S., Maszczyk, A., Czuba, M., Michalczyk, M., & Zydek, G. (2014). The effects of a ketogenic diet on exercise metabolism and physical performance in off-road cyclists. Nutrients, 6(7), 2493–2508. https://doi.org/10.3390/nu6072493
Zhang, S., Sun, S., Wei, X., Zhang, M., Chen, Y., Mao, X., Chen, G., & Liu, C. (2022). Short-term moderate caloric restriction in a high-fat diet alleviates obesity via AMPK/SIRT1 signaling in white adipocytes and liver. Food & nutrition research, 66, 10.29219/fnr.v66.7909. https://doi.org/10.29219/fnr.v66.7909
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