LA DIETA CETOGÉNICA COMO TERAPIA NUTRICIONAL ADYUVANTE EN PACIENTES CON GLIOBLASTOMA, UNA DESCRIPCIÓN TEÓRICA
DOI:
https://doi.org/10.32399/icuap.rdic.2448-5829.2024.Especial.1357Palabras clave:
Dieta cetogénica, cáncer, glioblastomaResumen
Esta revisión profundiza en las bases fisiológicas de la dieta cetogénica y su capacidad para influir en el entorno metabólico desfavorable que impulsa el crecimiento del Glioblastoma Multiforme. Mediante el análisis de investigaciones recientes, se aporta información sobre la implementación de la dieta cetogénica en pacientes con GBM. Al considerar factores como la composición nutricional, la duración del tratamiento y los resultados alcanzados, se muestran perspectivas alentadoras en términos de supervivencia y calidad de vida. Asimismo, se subraya la importancia de una supervisión médica cercana y de adaptar la dieta a las necesidades individuales para maximizar los beneficios. No obstante, a pesar de las observaciones prometedoras, se recalca la necesidad de futuras investigaciones que establezcan pautas clínicas sólidas y ofrezcan una comprensión más profunda del potencial de la dieta cetogénica como terapia complementaria contra el glioblastoma multiforme. En resumen, esta revisión proporciona información valiosa para profesionales de la salud, nutricionistas y científicos comprometidos en la búsqueda de enfoques innovadores destinados a mejorar los resultados en pacientes con tumores cerebrales primarios como el Glioblastoma Multiforme.
Citas
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Champ, C. E., Palmer, J. D., Volek, J. S., Werner-Wasik, M., Andrews, D. W., Evans, J. J., Glass, J., Kim, L., & Shi, W. (2014). Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme. J Neurooncol, 117(1), 125-131. https://doi.org/10.1007/s11060-014-1362-0
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Ding, J. D., Yao, K., Wang, P. F., & Yan, C. X. (2018). Clinical significance of prognostic nutritional index in patients with glioblastomas. Medicine (Baltimore), 97(48), e13218. https://doi.org/10.1097/MD.0000000000013218
Dowis, K., & Banga, S. (2021). The Potential Health Benefits of the Ketogenic Diet: A Narrative Review. Nutrients, 13(5). https://doi.org/10.3390/nu13051654
Elsakka, A. M. A., Bary, M. A., Abdelzaher, E., Elnaggar, M., Kalamian, M., Mukherjee, P., & Seyfried, T. N. (2018). Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up. Front Nutr, 5, 20. https://doi.org/10.3389/fnut.2018.00020
Faraz, S., Pannullo, S., Rosenblum, M., Smith, A., & Wernicke, A. G. (2016). Long-term survival in a patient with glioblastoma on antipsychotic therapy for schizophrenia: a case report and literature review. Ther Adv Med Oncol, 8(6), 421-428. https://doi.org/10.1177/1758834016659791
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Hohn, S., Dozieres-Puyravel, B., & Auvin, S. (2019). History of dietary treatment from Wilder's hypothesis to the first open studies in the 1920s. Epilepsy Behav, 101(Pt A), 106588. https://doi.org/10.1016/j.yebeh.2019.106588
Huq, S., Khalafallah, A. M., Botros, D., Oliveira, L. A. P., White, T., Dux, H., Jimenez, A. E., & Mukherjee, D. (2021). The Prognostic Impact of Nutritional Status on Postoperative Outcomes in Glioblastoma. World Neurosurg, 146, e865-e875. https://doi.org/10.1016/j.wneu.2020.11.033
Ibarretxe, D., & Masana, L. (2021). Metabolismo de los triglicéridos y clasificación de las hipertrigliceridemias. Clínica e Investigación en Arteriosclerosis, 33, 1-6. https://doi.org/https://doi.org/10.1016/j.arteri.2021.02.004
Jager-Wittenaar, H., & Ottery, F. D. (2017). Assessing nutritional status in cancer: role of the Patient-Generated Subjective Global Assessment. Curr Opin Clin Nutr Metab Care, 20(5), 322-329. https://doi.org/10.1097/MCO.0000000000000389
Jiang, Z., Zhang, X., Yang, L., Li, Z., & Qin, W. (2016). Effect of restricted protein diet supplemented with keto analogues in chronic kidney disease: a systematic review and meta-analysis. Int Urol Nephrol, 48(3), 409-418. https://doi.org/10.1007/s11255-015-1170-2
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2024-04-24
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Matadamas Pérez , D. G. ., Zarza Camacho , C. F. ., Morán Raya , C. ., Rivera Castro, M. E. ., Díaz Fonseca , A. D. ., & Bravo-Benítez, J. M. . (2024). LA DIETA CETOGÉNICA COMO TERAPIA NUTRICIONAL ADYUVANTE EN PACIENTES CON GLIOBLASTOMA, UNA DESCRIPCIÓN TEÓRICA. RD-ICUAP, 10(29), 11–26. https://doi.org/10.32399/icuap.rdic.2448-5829.2024.Especial.1357
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