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Entre ajolotes y mascarillas

Probiotics used in dermatology: therapeutic potential in inflammatory skin diseases

Submitted
November 10, 2021
Published
September 15, 2021

Abstract

Probiotics are live microorganisms beneficial to health when ingested properly. The gut microbiota has been shown to play a vital role in the regulation of immune function and physical health and so a strengthened skin microbiota limits the ability of pathogenic bacteria to start and spread an opportunistic infection. Thus, different clinical studies have shown that probiotics are effective against a wide range of common inflammatory skin diseases such as atopic dermatitis or acne, promising great potential in the dermatological area.

References

  1. Agudelo-Ochoa, G. M., Valdés-Duque, B. E., Giraldo-Giraldo, N. A., Jaillier-Ramírez, A. M., Giraldo-Villa, A., Acevedo-Castaño, I., Yepes-Molina, M. A., Barbosa-Barbosa, J., & Benítez-Paéz, A. (2020). Gut microbiota profiles in critically ill patients, potential biomarkers and risk variables for sepsis. Gut Microbes, 12(1), 1–16. https://doi.org/10.1080/19490976.2019.1707610
  2. Bowe, W. P., & Logan, A. C. (2011). Acne vulgaris, probiotics and the gut-brain-skin axis - Back to the future? Gut Pathogens, 3(1), 1–11. https://doi.org/10.1186/1757-4749-3-1
  3. Bustamante, M., Dave Oomah, B., Oliveira, W. P., Burgos-Díaz, C., Rubilar, M., Shene, C., & Bustamante marielabustamante, M. (2020). Probiotics and prebiotics potential for the care of skin, female urogenital tract, and respiratory tract GOS Galactooligosaccharides LRT Lower respiratory tract MJ Megajoule QoL Quality of life RTIs Respiratory tract infections SCORAD Scoring Atopic Derma. Folia Microbiologica, 245–264. https://doi.org/10.1007/s12223-019-00759-3
  4. Chen, Y. E., & Tsao, H. (2013). The skin microbiome: Current perspectives and future challenges. Journal of the American Academy of Dermatology, 69(1), 143-155.e3. https://doi.org/10.1016/j.jaad.2013.01.016
  5. Doron, S., & Snydman, D. R. (2015). Risk and safety of probiotics. Clinical Infectious Diseases, 60(Suppl 2), S129–S134. https://doi.org/10.1093/cid/civ085
  6. Fuchs-Tarlovsky, V., Marquez-Barba, M. F., & Sriram, K. (2016). Probiotics in dermatologic practice. Nutrition, 32(3), 289–295. https://doi.org/10.1016/j.nut.2015.09.001
  7. Ganji-Arjenaki, M., & Rafieian-Kopaei, M. (2018). Probiotics are a good choice in remission of inflammatory bowel diseases: A meta analysis and systematic review. Journal of Cellular Physiology, 233(3), 2091–2103. https://doi.org/10.1002/jcp.25911
  8. Hillion, M., Mijouin, L., Jaouen, T., Barreau, M., Meunier, P., Lefeuvre, L., Lati, E., Chevalier, S., & Feuilloley, M. G. J. (2013). Comparative study of normal and sensitive skin aerobic bacterial populations. MicrobiologyOpen, 2(6), 953–961. https://doi.org/10.1002/mbo3.138
  9. Jan, R. L., Yeh, K. C., Hsieh, M. H., Lin, Y. L., Kao, H. F., Li, P. H., Chang, Y. S., & Wang, J. Y. (2012). Lactobacillus gasseri suppresses Th17 pro-inflammatory response and attenuates allergen-induced airway inflammation in a mouse model of allergic asthma. British Journal of Nutrition, 108(1), 130–139. https://doi.org/10.1017/S0007114511005265
  10. Kang, B. S., Seo, J. G., Lee, G. S., Kim, J. H., Kim, S. Y., Han, Y. W., Kang, H., Kim, H. O., Rhee, J. H., Chung, M. J., & Park, Y. M. (2009). Antimicrobial activity of enterocins from Enterococcus faecalis SL-5 against Propionibacterium acnes, the causative agent in acne vulgaris, and its therapeutic effect. Journal of Microbiology, 47(1), 101–109. https://doi.org/10.1007/s12275-008-0179-y
  11. Kim, J., Ko, Y., Park, Y. K., Kim, N. I., Ha, W. K., & Cho, Y. (2010). Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition, 26(9), 902–909. https://doi.org/10.1016/j.nut.2010.05.011
  12. Knackstedt, R., Knackstedt, T., & Gatherwright, J. (2020). The role of topical probiotics in skin conditions: A systematic review of animal and human studies and implications for future therapies. Experimental Dermatology, 29(1), 15–21. https://doi.org/10.1111/exd.14032
  13. Kwon, H. K., Lee, C. G., So, J. S., Chae, C. S., Hwang, J. S., Sahoo, A., Nam, J. H., Rhee, J. H., Hwang, K. C., & Im, S. H. (2010). Generation of regulatory dendritic cells and CD4+Foxp3 + T cells by probiotics administration suppresses immune disorders. Proceedings of the National Academy of Sciences of the United States of America, 107(5), 2159–2164. https://doi.org/10.1073/pnas.0904055107
  14. Mottin, V. H. M., & Suyenaga, E. S. (2018). An approach on the potential use of probiotics in the treatment of skin conditions: acne and atopic dermatitis. International Journal of Dermatology, 57(12), 1425–1432. https://doi.org/10.1111/ijd.13972
  15. Rather, I. A., Bajpai, V. K., Kumar, S., Lim, J., Paek, W. K., & Park, Y. H. (2016). Probiotics and atopic dermatitis: An overview. Frontiers in Microbiology, 7(APR), 1–7. https://doi.org/10.3389/fmicb.2016.00507
  16. Silva, D. R., Sardi, J. de C. O., Pitangui, N. de S., Roque, S. M., Silva, A. C. B. da, & Rosalen, P. L. (2020). Probiotics as an alternative antimicrobial therapy: Current reality and future directions. Journal of Functional Foods, 73(July), 104080. https://doi.org/10.1016/j.jff.2020.104080
  17. Yu, Y., Dunaway, S., Champer, J., Kim, J., & Alikhan, A. (2020). Changing our microbiome: probiotics in dermatology. British Journal of Dermatology, 182(1), 39–46. https://doi.org/10.1111/bjd.18088