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Fashion and biotechnology are topics that we do not usually think are related. However, current efforts are being made to combine design and biotechnology, emerging in the creation of different bio-textiles that seek to change conventional practices in terms of production and consumption in the fashion industry, which have harmed the environment. Bio-textiles are produced from microorganisms, making biomaterials more sustainable, less polluting, and potentially scalable. The present work aims to present what a bio-textile is, its applications in the fashion industry, the work of one of the pioneering women in making garments with bacterial cellulose, and examples of projects that already work with these biomaterials, as well as talking about its limitations and importance in the future.